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K&A - Maintenance Schedule

 This guide outlines recommended maintenance tasks and their ideal frequency.

🗓️ Weekly Maintenance

Check Reagent & Amidite Levels

  • Verify that all bottles are filled to appropriate levels

  • Refill or replace any reagents nearing depletion

Visual Inspection

  • Inspect the instrument for leaks, salt buildup, or chemical residue

  • Confirm that no hoses or fittings appear loose or damaged

Run Shut Down Procedure

  • If the instrument will not be used for some time. perform a complete flush of the fluid lines using the Shutdown Procedure in the Manual Control Screen.

🗓️ Monthly Maintenance

O-Ring and Seal Inspection

  • Inspect seals on amidite and reagent bottle caps


Check Pressure Stability

  • Refer to THIS VIDEO

  • Pressurize the system and monitor for pressure drop

  • A drop of more than 0.5 psi in 1 minute may indicate a leak


Valve Function Test

  • Use manual valve control to ensure each valve actuates with a clear click

  • Check for steady flow and even delivery from each valve

Flow Test

  • Perform a calibration check using a precision balance and graduated vial. Refer to THIS PAGE.

  • Dispense and measure output for each valve

  • Address any inconsistencies.

  • If a Valve Replacement is necessary refer to THIS VIDEO. 

Remove water and check oil level of Compressor

  • Refer to THIS PAGE

  • Turn off the compressor

  • Hold a collection vial underneath the line for the purge valve
  • Open the Manual Water Remove Switch to remove all water
  • Close the switch
  • Turn the compressor back on 

🗓️ 6 Month Maintenance

Inspect Manifolds and Internal Connections

  • Open the instrument and inspect reagent manifolds and pneumatic fittings

  • Look for signs of wear, leaks, or corrosion.

Replace Wear Components

  • Replace any valves  with inconsistent performance. Refer to THIS VIDEO.

  • Replace Main Delivery Manifold Membrane. Refer to THIS PAGE.

Software Backup

  • Backup configuration files and job data


🗓️ Annual Maintenance

Replace Wear Components

  • Replace O-rings, seals, and any tubing showing signs of fatigue

  • Replace any valves or regulators with inconsistent performance. Refer to THIS VIDEO.

  • Replace ALL Membranes (Liquid Delivery Manifold and Waste Manifolds). Refer to THIS PAGE.

 Deep System Clean

  • Flush all fluidic paths thoroughly

  • Clean interior and exterior surfaces using appropriate solvents


🧪 Additional Tips

  • Use only anhydrous acetonitrile or other compatible solvents

  • Always wear appropriate PPE during maintenance procedures

  • Log all maintenance actions in the system service log