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Sierra Biosystems Support Center
Troubleshooting & Errors
Troubleshooting & Errors
Look at troubleshooting suggestions to common issues and error codes
Software Errors & Communication Issues
How to Help Us Identify Software or Computer Issues
Troubleshooting NexusDB Server Issues
Shasta Software Errors
Troubleshooting Server Connection Errors
K&A Software Errors
Chemistry and Protocol-Related Issues
Common Mass Impurities Observed in Oligonucleotide Analysis
Optimizing Protocols in K&A or Shasta Software
Sulfurization Strategies for Phosphorothioate (PS) Oligonucleotide Synthesis
Troubleshooting Poor Yields, Impurities and Methods
K&A - Preventative Maintenance & Quick Fixes
K&A - Maintenance Schedule
K&A - How to Perform a Flow Test
K&A - Replacing or Adding a Bottle Cap
K&A - Understanding Trityl Monitors
K&A - How To Change a Membrane
K&A - Monthly Compressor Maintenance Procedure
K&A - Understanding the Shut Down Procedure
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Shasta - Preventative Maintenance & Quick Fixes
Shasta - Replacing Bottle-to-Valve Amidite Line
Shasta - Monthly Maintenance Procedure
Shasta - How to Replace a Clogged Line or Valve on a Shasta Synthesizer
How to Minimize Argon Usage on Shasta Systems
Shasta - Hardware Issues
Synthesis Slowing Down Over Time – Possible Y‑Axis Cable Connection Issue
