--- title: Sierra Biosystems Support Center description: Sierra Biosystems Support Center --- [Skip to content](https://support.sierrabio.com#main-content) English Show submenu for translations ![](https://support.sierrabio.com/hs-fs/hubfs/JPG%20file%20-02.jpg?width=2000&height=1125&name=JPG%20file%20-02.jpg) Open main navigation Close main navigation - English Show submenu for translations - [Contact us](mailto:support@sierrabio.com) [Contact us](mailto:support@sierrabio.com) How can we help you? - There are no suggestions because the search field is empty. ### [Pre-Installation & Installation Essential resources to help you prepare for your Shasta or K&A System](https://support.sierrabio.com/pre-installation-installation?hsLang=en) - [K&A Pre-Installation Requirements](https://support.sierrabio.com/kanda-synthesizer-pre-installation-requirements-?hsLang=en) - [Shasta Synthesizer Pre-Installation Requirements](https://support.sierrabio.com/shasta-synthesizer-pre-installation-requirements?hsLang=en) - [Pre-Installation Checklist](https://support.sierrabio.com/pre-installation-checklist?hsLang=en) - [Choosing the Correct Bottle Cap Size for Reagents and Amidites](https://support.sierrabio.com/choosing-the-correct-bottle-cap-size-for-reagents-and-amidites?hsLang=en) [See more](https://support.sierrabio.com/pre-installation-installation?hsLang=en) ### [Troubleshooting & Errors Look at troubleshooting suggestions to common issues and error codes](https://support.sierrabio.com/troubleshooting-errors?hsLang=en) - [Shasta Software Errors](https://support.sierrabio.com/shasta-software-errors?hsLang=en) - [K&A Software Errors](https://support.sierrabio.com/ka-software-errors?hsLang=en) - [K&A - How to Perform a Flow Test](https://support.sierrabio.com/ka-how-to-perform-a-flow-test?hsLang=en) - [How to Minimize Argon Usage on Shasta Systems](https://support.sierrabio.com/how-to-minimize-argon-usage-on-shasta-systems?hsLang=en) [See more](https://support.sierrabio.com/troubleshooting-errors?hsLang=en) ### [Training Videos and Guides All video-based resources including: training series, Maintenance tutorials, Quick start videos](https://support.sierrabio.com/training-videos-and-guides?hsLang=en) - [01. Shasta Software - Introduction & Performing a Synthesis](https://support.sierrabio.com/shasta-software-introduction-performing-a-synthesis?hsLang=en) - [01. K&A Next Gen Software - Overview](https://support.sierrabio.com/kanextgen-software-training-video?hsLang=en) [See more](https://support.sierrabio.com/training-videos-and-guides?hsLang=en) ### [Software Updates & Release Notes Software Updates, Release Notes and Installation instructions](https://support.sierrabio.com/software-updates-release-notes?hsLang=en) - [How to Perform a Backup or Restore in KA or Shasta Software](https://support.sierrabio.com/how-to-perform-a-backup-or-restore-in-ka-or-shasta-software?hsLang=en) - [How to Set Up Network Communication with K&A or Shasta Software](https://support.sierrabio.com/how-to-set-up-network-communication-with-ka-or-shasta-software?hsLang=en) - [K&A Labs Software Release Notes (Latest v 0.0.16.6)](https://support.sierrabio.com/ka-labs-software-release-notes-all?hsLang=en) - [Shasta Software - Release Notes - V. 2.5.10](https://support.sierrabio.com/shasta-software-release-notes-updated?hsLang=en) [See more](https://support.sierrabio.com/software-updates-release-notes?hsLang=en) ### [Product Documentation & Policies Official manuals, specifications, warranty information, and service contracts for Sierra Biosystems instruments.](https://support.sierrabio.com/product-documentation-policies?hsLang=en) - [Sierra Limited Warranty](https://support.sierrabio.com/sierra-limited-warranty?hsLang=en) - [Sierra Service Contracts: Standard and Premium](https://support.sierrabio.com/sierra-service-contracts?hsLang=en) - [Shasta - Technical Documents](https://support.sierrabio.com/shasta-technical-documents?hsLang=en) - [K&A - Technical Documents](https://support.sierrabio.com/ka-technical-documents?hsLang=en) [See more](https://support.sierrabio.com/product-documentation-policies?hsLang=en) ### [Oligonucleotide Chemistry & Methods This section covers the end-to-end chemistry steps and recommended workflows for oligonucleotide synthesis and handling.](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en) - [Purification Methods for Oligonucleotides](https://support.sierrabio.com/purification-methods-for-oligonucleotides?hsLang=en) - [Cleavage and Deprotection of Oligonucleotides](https://support.sierrabio.com/cleavage-and-deprotection-of-oligonucleotides?hsLang=en) - [How to Analyze and QC Oligonucleotide Samples?](https://support.sierrabio.com/how-to-analyze-and-qc-oligonucleotide-samples?hsLang=en) - [Quantitation of Oligonucleotides](https://support.sierrabio.com/quantitation-of-oligonucleotides?hsLang=en) [See more](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en) ### [Support & Contact Submit a Ticket, Software Bug Report or Feature Request.](https://support.sierrabio.com/support-contact?hsLang=en) - [🎫 Submit a Bug Report of Feature Request](https://support.sierrabio.com/submit-a-bug-report-of-feature-request?hsLang=en) - [🎫 Submit a Support Ticket](https://support.sierrabio.com/submit-a-support-ticket?hsLang=en) [See more](https://support.sierrabio.com/support-contact?hsLang=en) [![](https://support.sierrabio.com/hs-fs/hubfs/JPG%20file%20-02.jpg?width=2000&height=1125&name=JPG%20file%20-02.jpg)](http://sierrabio.com) [mailto:Support@sierrabio.com](mailto:Support@sierrabio.com) Copyright © 2025, Sierra BioSystems