--- title: Shasta Software - Release Notes - V. 2.5.10 description: The release notes for Shasta software version 2.5.9 --- [Skip to content](https://support.sierrabio.com/shasta-software-release-notes-updated#main-content) English Show submenu for translations ![](https://support.sierrabio.com/hs-fs/hubfs/JPG%20file%20-02.jpg?width=2000&height=1125&name=JPG%20file%20-02.jpg) Open main navigation Close main navigation - English Show submenu for translations - [Contact us](mailto:support@sierrabio.com) [Contact us](mailto:support@sierrabio.com) How can we help you? - There are no suggestions because the search field is empty. 1. [Sierra Biosystems Support Center](https://support.sierrabio.com/?hsLang=en) 2. [Software Updates & Release Notes](https://support.sierrabio.com/software-updates-release-notes?hsLang=en) 3. [Release Notes](https://support.sierrabio.com/software-updates-release-notes?hsLang=en#release-notes) June 25, 2026 # Shasta Software - Release Notes - V. 2.5.10 ## This article summarizes the software revisions, feature enhancements, and corrections implemented between versions v2.5.5 and v2.5.10   ### **Software Release Notes** --- #### **Revision History** ### **Version 2.5.5** - Corrected button order in the **Sequence Editor** — the Import and Export buttons had been reversed in a prior update. - Added a new configuration option to **enable pre-priming all tips** prior to each dispense pass (applicable to *Standard* and *Meta* protocols only). - Updated **Run Synthesis** to automatically **prime all tips ready for dispense** before the start of each dispense-pass series (*Standard* and *Meta* protocols only). --- ### **Version 2.5.6** - Modified **Run Synthesis** pressure monitoring behavior: - When pressure goes out of range, the system now **logs the event silently** instead of displaying an interrupting dialog. - The synthesis automatically continues once pressure returns to the acceptable range. - Other pausable conditions (e.g., *Lid Open*, *Leak Detected*) will still trigger user dialogs requiring acknowledgment before resuming. --- ### **Version 2.5.7** - Updated **Backup/Restore** functionality to no longer remember the previous archive path or filename. - Added a new configuration option to **restrict plate movement** unless chamber pressure is within acceptable limits. - Enhanced the **Manual Control**, **Priming**, and **Calibrate Position** screens to: - Display current **lid switch** and **chamber pressure** status. - Only allow plate motion when both **lid closed** and **pressure OK** conditions are met, based on configuration settings. - Updated **Dispense Calibration** to move the plate only when lid and pressure conditions are verified as good. --- ### **Version 2.5.8** - Added advanced **Run Synthesis controls**, allowing users to: - **Start synthesis** from a specific base. - **Pause** before a specified base. - **Pause** automatically after a defined number of hours or minutes. --- ### **Version 2.5.9** - Modified **Run Synthesis** to disable *Pause Before Base X* and *Pause After X Hours/Minutes* features when running **MAP protocols**.   --- ### **Version 2.5.10** — **Validated Build** - Changed the Run Synthesis to move the plate to the "View" position at the end of the synthesis instead of a neutral (x=100, y=100) position. **Status:** ✅ *Validated build for production and field use (v2.5.10)* --- #### **Summary of Key Improvements** - Enhanced **pressure and motion safety interlocks** for improved operator protection. - Added **flexible synthesis controls** (start/pause/resume logic). - Improved **UI consistency** across Manual Control, Priming, and Calibration screens. - Reduced potential for synthesis interruptions due to transient pressure fluctuations. - Improved **pre-dispense priming reliability** for Standard and Meta protocols. - [Pre-Installation & Installation](https://support.sierrabio.com/pre-installation-installation?hsLang=en#main-content) - 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