Skip to content
English
Sign in
Contact us
  • There are no suggestions because the search field is empty.

K&A Labs Software Release Notes (Latest v 0.0.16.6)

This article summarizes all software revisions, enhancements, and bug fixes 

K&A Labs Software Release Notes Validated Build: 0.0.16.6 | Release Date: March 2026

What's new in 0.0.16.6 (current release)

  • Volume estimation and flow rates

  • The Volume Estimate button has been restored to the Run Synthesis screen. It displays all reagents and amidites used in your sequence along with estimated volumes, calculated using the flow rates configured on the Flow Rates screen.

  • If a reagent or amidite is missing a flow rate for its assigned port, its estimated volume will display as zero — no warning will be shown, so please verify all flow rates are configured before running an estimate.

  • Flow rates can now be exported as an XLSX file directly from the Flow Rates screen.

  • Mixed amidites

  • Run Synthesis now includes a mixing chamber feature to support mixed amidites.

Version history

Version 0.0.15.4 ✅ Previously validated build (October 2025)

  • Removed redundant Manual Control code introduced in earlier revisions.
  • Adjusted Run Synthesis to bypass Meta Pre-Process steps when starting mid-sequence.
  • Corrected Cycle and Section total calculations that were affecting completion percentages.
  • Ensured proper Meta protocol activation when initiating synthesis from a later base.

Version 0.0.15.2

  • Disabled the "Start at base" option once synthesis has begun.
  • Removed deprecated options: Auto Prime and Add ACN to completed columns.
  • Added automatic Manifold Wash when resuming from a pause.
  • Adjusted cycle and base count logic for mid-sequence starts.
  • Corrected the completion time estimate when starting at a later base.

Version 0.0.15.0

Added enhanced Run Synthesis control options:

  • Start synthesis from a specific base position.
  • Pause before a designated base.
  • Set an automatic pause after a defined run time (hours and minutes).

Version 0.0.14.3

  • Temporarily disabled the firmware version check pending further validation (0.0.14.1).
  • Increased multi-port priming mix time from 20 ms to 40 ms (0.0.14.2).
  • Corrected the firmware command used to trigger injections during priming (0.0.14.3).

Version 0.0.14.0

  • Added a configuration option for Mid-Synthesis Priming.
  • Updated Run Synthesis to perform priming before each protocol section, activating the relevant reagent/amidite and first active column.

Version 0.0.13.2

  • Fixed a Hold-to-Prime bug that was referencing an incorrect function.
  • Confirmed full implementation of customizable per-input priming times.

Version 0.0.13.0

  • Introduced a Priming feature allowing individual input lines to prime to Waste for defined durations.

Version 0.0.12.0

  • Modified Backup/Restore behavior to no longer retain the prior file path or archive name.
  • Corrected valve numbering for the H-4 configuration.

Version 0.0.11.0

  • Added configuration control for Reverse Purge column batch size (1, 2, or 4 columns).
  • Updated Run Synthesis logic to handle column grouping accordingly.

Version 0.0.10.0

  • Fixed a software lock-up that occurred when Stop was pressed during pre-synthesis. The Abort button now remains available until synthesis begins.
  • Added a pre-run check confirming that all reagents and amidites in the sequence are assigned in the configuration.

Version 0.0.9.0

  • Implemented center-out injection behavior in Run Synthesis for H-28 and H-32 models.
  • Resolved an issue where purges continued running on completed columns, which could cause cross-contamination.

Version 0.0.8.11

  • Fixed an issue where valves remained open during the Wash TM function.

Version 0.0.8.10

  • Added valve definitions to support H-28 and H-32 instruments.
  • Updated Manual Control to accommodate the H-28 and H-32 center-out injection pattern.
  • Modified the Wash TM process to allow single or dual injection based on configuration.

Version 0.0.8.9

  • Fixed an issue where Reagent/Amidite drop-down lists failed to update after a database restore or server change.
  • Corrected a case-sensitivity mismatch between sequence names and amidite configuration names during synthesis.

Summary of improvements across all releases

  • Flexible synthesis control: start from a specific base, pause mid-run, and resume with automatic manifold wash.
  • Expanded priming options: manual, pre-synthesis, and mid-synthesis priming with per-input timing.
  • Volume estimation with flow rate export for run planning.
  • Support for H-4, H-28, and H-32 instruments.
  • Reduced risk of cross-contamination and unintended valve behavior.
  • Improved error handling, run time accuracy, and completion percentage tracking.