--- title: K&A Labs Software Release Notes - V. 0.0.9.0 description: The release notes for K&A software version 0.0.8.8 --- [Skip to content](https://support.sierrabio.com/ka-labs-software-release-notes#main-content) English Show submenu for translations ![](https://support.sierrabio.com/hs-fs/hubfs/JPG%20file%20-02.jpg?width=2000&height=1125&name=JPG%20file%20-02.jpg) Open main navigation Close main navigation - English Show submenu for translations - [Contact us](mailto:support@sierrabio.com) [Contact us](mailto:support@sierrabio.com) How can we help you? - There are no suggestions because the search field is empty. 1. [Sierra Biosystems Support Center](https://support.sierrabio.com/?hsLang=en) 2. [Software Updates & Release Notes](https://support.sierrabio.com/software-updates-release-notes?hsLang=en) 3. [Release Notes](https://support.sierrabio.com/software-updates-release-notes?hsLang=en#release-notes) August 8, 2025 # K&A Labs Software Release Notes - V. 0.0.9.0 ## The following release notes outline all enhancements, fixes, and feature additions made across versions of the K&A Labs software.   ### **v0.0.9.0 - July  2025** - **H-28 and H-32 Support:** Added code to Run Synthesis to support the H-28 and H-32 injections pattern of center-out. - **Single Column Purging:** Fixed an issue where purges during a synthesis would purge all columns, including completed columns leading to cross-contamination. --- ### **v0.0.8.8** - **Improved Synthesis Logic**: Amidite/activator injections are now performed one column at a time to ensure precision and stability. - **Manual Control Column Sorting**: Columns are now processed in sequential order internally, regardless of their Port Assignment position. - **Shutdown Procedure**: A guided shutdown workflow has been added to the Manual Control screen. --- ### **v0.0.8.7** - **Histogram Fix**: Resolved an issue where completed columns were still contributing data to the Histogram chart. - **Cycle Count Logic**: Max cycle count now excludes Pre, DMT, and Post steps unless required by at least one column. - **Cycle Hang Prevention**: Corrected a bug where synthesis would hang during Pre, DMT, or Post steps if non-participating columns were not bypassed correctly. --- ### **v0.0.8.6** - **H-2 Analog Port Adjustment**: Configured analog trityl reading ports to use ports 7 & 8 (instead of 1 & 2) for H-2 instruments. --- ### **v0.0.8.5 – v0.0.8.3** - **Histogram Cap**: Yield and Efficiency percentages are now capped at 100%. - **ASWY Title Update**: Coupling Efficiency graph title updated to "ASWY." - **ASWY Calculation Fix**: Corrected the ASWY calculation to use decimal (e.g., 0.73) instead of percentage value (e.g., 73%). --- ### **v0.0.8.1** - **Histogram Window Memory**: The Histogram screen will now remember its last size and position. - **Chart Labels Added**: Charts now include V2, Yield %, and Coupling Efficiency in their titles. --- ### **v0.0.8.0** - **Trityl Histogram Viewer**: A dedicated histogram viewer was added to the Run Synthesis screen to display trityl monitor data per cycle and per column. --- ### **v0.0.7.10** - **Sequence Column Sorting**: Columns in the Run Synthesis sequence list are now always ordered sequentially. - **Error Handling Fix**: Addressed a bug causing errors when trityl read values were updated for missing columns. --- ### **v0.0.7.9** - **H-2 Compatibility**: Run Synthesis now supports H-2 configuration. - **NetBIOS Support Removed**: Discontinued support for Named Pipes due to Microsoft’s removal of Remote Mailslots. --- ### **v0.0.7.8** - **Protocol Detail Fix**: Corrected a bug preventing Protocol Detail from loading in some cases. - **Manual Control H-2 Support**: Added compatibility for H-2 instruments in Manual Control. --- ### **v0.0.7.7** - **H-8SE Valve Assignments**: Added valve mapping for H-8SE. - **Trityl Analog Fix**: Adjusted column numbering to start from 0 for accurate analog trityl readings. --- ### **v0.0.7.5** - **Screen State Fix**: Prevented unintended re-enabling of certain screens during Run Synthesis. - **Trityl Formula Update**: Revised the formula for calculating trityl percentages during synthesis. --- ### **v0.0.7.4 – v0.0.7.3** - **Live TM Readings**: Added a TM % column to the sequence grid to show the most recent trityl monitor value. - **Gate Valve Activation Fix**: Ensured gate valves activate properly during the Wash TM function. - **Reverse Purge Improvement**: Reverse Purge now handles up to 4 columns at a time. --- ### **v0.0.7.2 – v0.0.7.1** - **Trityl Routing Updates**: - Only the first Deblock per cycle is sent to TM; others are discarded. - First Deblock purge now routes to TM. - **Pause Handling Fix**: Addressed issues with Pause After Repetition functionality. - **TM Valve Activation**: Fixed improper activation of certain trityl monitor valves. --- ### **v0.0.7.0** - **Trityl Monitor Enhancements**: - Deblock solution is now sent to TM during injection. - TM values are logged per column and cycle, with baseline normalization. - TM is emptied automatically after relevant cycles. --- ### **v0.0.6.6** - **Timing Synchronization Fixes**: Overhauled timing and `GetStatus` logic to resolve synchronization issues. --- ### **v0.0.6** - **Trityl Monitor Empty Time**: Configuration setting added to define trityl monitor empty duration in seconds. --- ### **v0.0.5** - **Port Assignment Updates**: - Updated manifold mappings for newer instrument models (H-8SE, H-8VLS, H-16, etc.). - PortAssign database records are now automatically updated. - **Dual Column Injection**: Added configuration option to enable dual injection. - **Run Synthesis Support**: Implemented support for both Standard and Meta protocols. --- ### **v0.0.4** - **Protocol Editor Update**: Supports new K&A command sets and timing. - **Sequence Editor Overhaul**: - Entries are now individual sequences with names. - Import/export enhanced to support multiple sequences via `.xlsx`. --- ### **v0.0.3** - **Manual Control Layout**: - Redesigned visual layout to better reflect real port/valve mapping. - Now supports all machine types except S-4. H-8+ is limited due to unknown valve numbers. --- ### **v0.0.2** - **Dynamic Manual Control**: - Manual Control now adapts dynamically to H-4 and H-6 models. - Pathways are drawn based on current configuration (active flow indication not yet implemented). - [Pre-Installation & Installation](https://support.sierrabio.com/pre-installation-installation?hsLang=en#main-content) - [Pre-Installation Requirements](https://support.sierrabio.com/pre-installation-installation?hsLang=en#pre-installation-requirements) - [Site & Lab Preparation](https://support.sierrabio.com/pre-installation-installation?hsLang=en#site-lab-preparation) - [Installation & Initial Setup](https://support.sierrabio.com/pre-installation-installation?hsLang=en#installation-initial-setup) - [Troubleshooting & Errors](https://support.sierrabio.com/troubleshooting-errors?hsLang=en#main-content) - [Software Errors & Communication Issues](https://support.sierrabio.com/troubleshooting-errors?hsLang=en#software-errors-communication-issues) - [Chemistry and Protocol-Related Issues](https://support.sierrabio.com/troubleshooting-errors?hsLang=en#chemistry-and-protocol-related-issues) - [K&A - Preventative Maintenance & Quick Fixes](https://support.sierrabio.com/troubleshooting-errors?hsLang=en#ka-preventative-maintenance-quick-fixes) - [Shasta - Preventative Maintenance & Quick Fixes](https://support.sierrabio.com/troubleshooting-errors?hsLang=en#shasta-preventative-maintenance-quick-fixes) - [Shasta - Hardware Issues](https://support.sierrabio.com/troubleshooting-errors?hsLang=en#shasta-hardware-issues) - [Training Videos and Guides](https://support.sierrabio.com/training-videos-and-guides?hsLang=en#main-content) - [Shasta Software](https://support.sierrabio.com/training-videos-and-guides?hsLang=en#shasta-software) - [K&A Next Gen Software](https://support.sierrabio.com/training-videos-and-guides?hsLang=en#ka-next-gen-software) - [K&A Legacy Software](https://support.sierrabio.com/training-videos-and-guides?hsLang=en#ka-legacy-software) - [K&A - Troubleshooting Videos](https://support.sierrabio.com/training-videos-and-guides?hsLang=en#ka-troubleshooting-videos) - [Shasta - Troubleshooting Videos](https://support.sierrabio.com/training-videos-and-guides?hsLang=en#shasta-troubleshooting-videos) - [Software Updates & Release Notes](https://support.sierrabio.com/software-updates-release-notes?hsLang=en#main-content) - [Release Notes](https://support.sierrabio.com/software-updates-release-notes?hsLang=en#release-notes) - [Downloads](https://support.sierrabio.com/software-updates-release-notes?hsLang=en#downloads) - [Update Instructions](https://support.sierrabio.com/software-updates-release-notes?hsLang=en#update-instructions) - [Product Documentation & Policies](https://support.sierrabio.com/product-documentation-policies?hsLang=en#main-content) - [Technical Documentation](https://support.sierrabio.com/product-documentation-policies?hsLang=en#technical-documentation) - [Specifications](https://support.sierrabio.com/product-documentation-policies?hsLang=en#specifications) - [Warranty & Service](https://support.sierrabio.com/product-documentation-policies?hsLang=en#warranty-service) - [Oligonucleotide Chemistry & Methods](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en#main-content) - [Synthesis & Strategy](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en#synthesis-strategy) - [Post-Synthesis Processing](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en#post-synthesis-processing) - [Quantitation & QC](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en#quantitation-qc) - [Special Topics](https://support.sierrabio.com/oligonucleotide-chemistry-methods?hsLang=en#special-topics) - [Support & Contact](https://support.sierrabio.com/support-contact?hsLang=en) - [Uncategorized](https://support.sierrabio.com/uncategorized?hsLang=en) [![](https://support.sierrabio.com/hs-fs/hubfs/JPG%20file%20-02.jpg?width=2000&height=1125&name=JPG%20file%20-02.jpg)](http://sierrabio.com) [mailto:Support@sierrabio.com](mailto:Support@sierrabio.com) Copyright © 2025, Sierra BioSystems