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08. K&A Next Gen Software - Backbone Modifications

How to specify backbone modifications, such as phosphorothioate linkages, using sequence punctuation. Walkthrough video (1:14).

How to specify backbone modifications, such as phosphorothioate linkages, using sequence punctuation.



Applies to

  • All K&A H-series instruments (H-2 through H-32) running KA_Labs 0.0.18.0.

What this video covers

  • What sequence punctuation means in KA_Labs.
  • How to specify a phosphorothioate (PS) linkage.
  • How to build a mixed backbone within one sequence.

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Last reviewed: 27 August 2026. Owner: Harold Devoz, Director of Field Operations. Applies to KA_Labs 0.0.18.0.